Linezolid CAS 165800-03-3 Assay 98.0~102.0%
Shanghai Ruifu Chemical Co., Ltd. is the leading manufacturer of Linezolid (CAS: 165800-03-3) with high quality. Ruifu Chemical can provide worldwide delivery, competitive price, excellent service, small and bulk quantities available. Purchase Linezolid (CAS: 165800-03-3), Please contact: alvin@ruifuchem.com
| Linezolid | CAS 165800-03-3 |
| 3-Fluoro-4-Morpholinoaniline | CAS 93246-53-8 |
| (S)-N-[2-(Acetyloxy)-3-Chloropropyl]acetamide | CAS 183905-31-9 |
| (R)-[3-(3-Fluoro-4-Morpholinophenyl)-2-Oxo-5-Oxazolidinyl]methyl Methanesulfonate | CAS 174649-09-3 |
| Phthalimide Potassium Salt | CAS 1074-82-4 |
| Chemical Name | Linezolid |
| Synonyms | (S)-N-[[3-(3-Fluoro-4-Morpholinophenyl)-2-Oxooxazolidin-5-yl]methyl]acetamide; N-[[(5S)-3-[3-Fluoro-4-(4-Morpholinyl)phenyl]-2-Oxo-5-Oxazolidinyl]methyl]-Acetamide; N-[[(5S)-3-(3-Fluoro-4-Morpholin-4-ylphenyl)-2-Oxo-1,3-Oxazolidin-5-yl]methyl]acetamide; Linospan; Linox; PNU 100766; U 100766; Zyvox; Zyvoxid |
| Stock Status | In Stock, Commercial Production |
| CAS Number | 165800-03-3 |
| Molecular Formula | C16H20FN3O4 |
| Molecular Weight | 337.35 g/mol |
| Melting Point | 177.0 to 181.0℃ |
| Density | 1.302±0.06 g/cm3 |
| Sensitive | Air Sensitive |
| Water Solubility | Insoluble in Water, 610 mg/l 25℃ |
| Solubility | Slightly Soluble in Dichloromethane; Insoluble in Ethanol |
| COA & MSDS | Available |
| Origin | Shanghai, China |
| Brand | Ruifu Chemical |
| Items | Inspection Standards | Results |
| Appearance | White to Off-White Crystalline Powder | White Crystalline Powder |
| Assay | 98.0~102.0% | 99.75% |
| Specific Rotation | -9.0° to -14.0° | -11.05° |
| Loss on Drying | <1.00% | 0.09% |
| Residue on Ignition | <0.20% | 0.07% |
| Related Substances | ||
| Max. Single Impurity | <0.50% | Complies |
| Any Unknown Impurity | <0.50% | Complies |
| Total Impurities | <1.00% | Complies |
| Heavy Metals | <20ppm | <20ppm |
| Infrared Spectrum | Consistent with Structure | Complies |
| 1H NMR Spectrum | Consistent with Structure | Complies |
| Conclusion | The product has been tested and complies with the given specifications | |
Package: Fluorinated Bottle, Aluminium foil bag, 25kg/Cardboard Drum, or according to customer's requirement.
Storage Condition: Keep the container tightly closed and store in a cool, dry and well-ventilated warehouse away from incompatible substances. Protect from light and moisture.
Shipping: Deliver to worldwide by air, by FedEx / DHL Express. Provide fast and reliable delivery.
How to Purchase? Please contact Dr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
15 Years Experience? We have more than 15 years of experience in the manufacture and export of a wide range of high quality pharmaceutical intermediates or fine chemicals.
Main Markets? Sell to domestic market, North America, Europe, India, Korea, Japanese, Australia, etc.
Advantages? Superior quality, affordable price, professional services and technical support, fast delivery.
Quality Assurance? Strict quality control system. Professional equipment for analysis include NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, K.F, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, etc.
Samples? Most products provide free samples for quality evaluation, shipping cost should be paid by customers.
Factory Audit? Factory audit welcome. Please make an appointment in advance.
MOQ? No MOQ. Small order is acceptable.
Delivery Time? If within stock, three days delivery guaranteed.
Transportation? By Express (FedEx, DHL), by Air, by Sea.
Documents? After sales service: COA, MOA, ROS, MSDS, etc. can be provided.
Custom Synthesis? Can provide custom synthesis services to best fit your research needs.
Payment Terms? Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T (Telex Transfer), PayPal, Western Union, etc.
Hazard Symbols Xn - Harmful
Risk Codes 20/21/22 - Harmful by inhalation, in contact with skin and if swallowed.
Safety Description S36 - Wear suitable protective clothing.
S24/25 - Avoid contact with skin and eyes.
WGK Germany 3
RTECS AC2720000
HS Code 2942000000
Linezolid (CAS: 165800-03-3) is a new type of azolidinone synthetic antibacterial drug developed and produced by Pharmacia & Upiohn Company (acquired by Pfizer), which was approved by FDA on April 18, 2000. This product is the first drug approved for the treatment of methicillin-resistant Staphylococcus aureus infection in the United States in 40 years. It was listed in my country in September 2007 and belongs to medical insurance Class B drugs.
For the treatment of Gram-positive (G +) bacteria caused infections, including concurrent bacteremia; nosocomial pneumonia; community-acquired pneumonia ( because bacteria are not the same,pneumonia is clinically divided into hospital-acquired pneumonia and community-acquired pneumonia) and concomitant bacteremia; it can be applied for the complexity of the skin and skin and soft tissue infections, including osteomyelitis in diabetic foot infections; uncomplicated skin and skin and soft tissue infections; it is also used for the treatment of vancomycin-resistant feces enterococci.
Oxazolidinone antibiotic. Inhibits bacterial protein synthesis prior to chain initiation. Displays potent antibacterial activity against a variety of multidrug-resistant gram-positive microbes in vitro and in vivo.
The mechanism of action is inhibition of protein synthesis, but at a stage different from that of other protein synthesis inhibitors. The oxazolidinones bind to the 23S rRNA of the 50S subparticle to prevent formation of a functional 70S initiation complex. It is considered to be bacteriostatic against enterococci and staphylococci but bacteriocidal against streptococci. Resistance to oxazolidinones is encountered in the clinic because of a mutation in the 23S rRNA. This is believed to distort the linezolid binding site. Gram-negative microorganisms are intrinsically resistant to linezolid because of the presence of endogenous efflux pumps that keep it from accumulating in the cells.
